1-Octane Sulfonic Acid Sodium Salt for HPLC

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Product Name 1-Octane Sulfonic Acid Sodium Salt for HPLC
Chemical Formula C8H17SO3Na
Molecular Weight 202.28 g/mol
Appearance White powder
Purity ≥ 98%
Solubility Soluble in water
Storage Store at room temperature
Usage Commonly used as an ion-pairing reagent in HPLC
Melting Point 193-196°C
Boiling Point Decomposes
CAS Number 1984-06-1
FAQ
What is 1-Octane Sulfonic Acid Sodium Salt and how is it used in HPLC applications?

1-Octane Sulfonic Acid Sodium Salt, also known as sodium octanesulfonate, is a common ion-pairing reagent used in High Performance Liquid Chromatography (HPLC). It is used to improve the separation of analytes in complex mixtures by altering the retention time and selectivity of the chromatographic separation.

How does 1-Octane Sulfonic Acid Sodium Salt improve HPLC separations?

The addition of 1-Octane Sulfonic Acid Sodium Salt to the mobile phase can significantly enhance the resolution of peaks in HPLC analyses. By forming ion pairs with analytes, it can alter their hydrophobicity and charge, leading to better separation and improved peak shape.

What are the advantages of using 1-Octane Sulfonic Acid Sodium Salt in HPLC?

Some of the key advantages of using 1-Octane Sulfonic Acid Sodium Salt in HPLC include improved peak shape, enhanced resolution of analytes, and increased selectivity of the separation. It is also cost-effective and compatible with various detection methods commonly used in HPLC.

How should 1-Octane Sulfonic Acid Sodium Salt be used in HPLC experiments?

1-Octane Sulfonic Acid Sodium Salt should be dissolved in the mobile phase at an appropriate concentration based on the specific requirements of the analysis. It is important to optimize the concentration of the reagent to achieve the desired separation while considering factors such as analyte properties and column chemistry.

Are there any precautions to consider when using 1-Octane Sulfonic Acid Sodium Salt in HPLC?

While 1-Octane Sulfonic Acid Sodium Salt is commonly used in HPLC applications, it is important to consider factors such as compatibility with the analytes of interest, column stability, and detection method sensitivity. It is recommended to perform method development and validation studies to ensure optimal results.
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