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| Product Name | N,N-Dimethylformamide for Headspace GC |
| Cas Number | 68-12-2 |
| Chemical Formula | C3H7NO |
| Molecular Weight | 73.09 g/mol |
| Appearance | Colorless liquid |
| Odor | Characteristic ammoniacal odor |
| Boiling Point | 153.3°C |
| Melting Point | -61.7°C |
| Density | 0.944 g/mL |
| Solubility | Miscible with water |
| Flash Point | 57°C |
| Auto Ignition Temperature | 510°C |
| Vapor Pressure | 0.6 kPa (20°C) |
| Purity | ≥99.5% |
| Applications | Used as a solvent in chemical reactions and as a headsapce GC (Gas Chromatography) standard |
| Hazard Class | Harmful if swallowed, causes skin and eye irritation |
FAQ
What is N,N-Dimethylformamide (DMF) and how is it used in Headspace GC
analysis?
N,N-Dimethylformamide (DMF) is a common solvent used in Headspace Gas Chromatography (GC) analysis. It is a polar aprotic solvent that is often used to dissolve solid or liquid samples for analysis by GC. DMF can help improve the sensitivity and accuracy of analysis by ensuring that the sample is completely dissolved and evenly dispersed in the headspace vial.
How does DMF improve the efficiency and sensitivity of Headspace GC analysis?
DMF is a versatile solvent that has several properties which make it ideal for use in Headspace GC analysis. Firstly, DMF has a high boiling point (153°C), which allows for samples to be heated to high temperatures without evaporating. This is important in Headspace GC analysis, where samples need to be heated to release volatile compounds into the gas phase. Additionally, DMF has a low vapor pressure, reducing the risk of sample loss during analysis. Finally, DMF is a good solvent for a wide range of compounds, making it suitable for a variety of sample types.
What are some key advantages of using DMF in Headspace GC analysis?
There are several advantages to using DMF in Headspace GC analysis. Firstly, DMF can dissolve a wide range of compounds, including polar and non-polar substances, making it versatile for different types of samples. Secondly, DMF's high boiling point means that it can be used at high temperatures without evaporating, ensuring the complete release of volatile compounds into the headspace vial. Finally, DMF's low vapor pressure reduces the risk of sample loss during analysis, improving the sensitivity and accuracy of the results.
Are there any limitations or considerations when using DMF in Headspace GC analysis?
While DMF is a versatile solvent for Headspace GC analysis, there are some limitations and considerations to keep in mind. DMF is a toxic solvent, so proper safety precautions should be taken when handling and disposing of it. Additionally, some compounds may not be soluble in DMF, so it may not be suitable for all sample types. It is also important to ensure that the DMF does not contaminate the GC system or interfere with the analysis, so regular maintenance and system checks are recommended.
How can I best utilize DMF in my Headspace GC analysis to achieve optimal results?
To achieve optimal results in Headspace GC analysis using DMF, it is important to follow some key guidelines. Firstly, ensure that the sample is completely dissolved in the DMF to ensure even dispersion in the headspace vial. Use the appropriate amount of DMF to dissolve the sample without oversaturating the solution. Optimize the heating temperature and equilibration time in the headspace vial to release volatile compounds efficiently. Regularly check and maintain the GC system to prevent contamination and ensure accurate results.
N,N-Dimethylformamide (DMF) is a common solvent used in Headspace Gas Chromatography (GC) analysis. It is a polar aprotic solvent that is often used to dissolve solid or liquid samples for analysis by GC. DMF can help improve the sensitivity and accuracy of analysis by ensuring that the sample is completely dissolved and evenly dispersed in the headspace vial.
How does DMF improve the efficiency and sensitivity of Headspace GC analysis?
DMF is a versatile solvent that has several properties which make it ideal for use in Headspace GC analysis. Firstly, DMF has a high boiling point (153°C), which allows for samples to be heated to high temperatures without evaporating. This is important in Headspace GC analysis, where samples need to be heated to release volatile compounds into the gas phase. Additionally, DMF has a low vapor pressure, reducing the risk of sample loss during analysis. Finally, DMF is a good solvent for a wide range of compounds, making it suitable for a variety of sample types.
What are some key advantages of using DMF in Headspace GC analysis?
There are several advantages to using DMF in Headspace GC analysis. Firstly, DMF can dissolve a wide range of compounds, including polar and non-polar substances, making it versatile for different types of samples. Secondly, DMF's high boiling point means that it can be used at high temperatures without evaporating, ensuring the complete release of volatile compounds into the headspace vial. Finally, DMF's low vapor pressure reduces the risk of sample loss during analysis, improving the sensitivity and accuracy of the results.
Are there any limitations or considerations when using DMF in Headspace GC analysis?
While DMF is a versatile solvent for Headspace GC analysis, there are some limitations and considerations to keep in mind. DMF is a toxic solvent, so proper safety precautions should be taken when handling and disposing of it. Additionally, some compounds may not be soluble in DMF, so it may not be suitable for all sample types. It is also important to ensure that the DMF does not contaminate the GC system or interfere with the analysis, so regular maintenance and system checks are recommended.
How can I best utilize DMF in my Headspace GC analysis to achieve optimal results?
To achieve optimal results in Headspace GC analysis using DMF, it is important to follow some key guidelines. Firstly, ensure that the sample is completely dissolved in the DMF to ensure even dispersion in the headspace vial. Use the appropriate amount of DMF to dissolve the sample without oversaturating the solution. Optimize the heating temperature and equilibration time in the headspace vial to release volatile compounds efficiently. Regularly check and maintain the GC system to prevent contamination and ensure accurate results.
