Tetrahydrofuran for UV, IR, HPLC, GPC

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Name Tetrahydrofuran for UV, IR, HPLC, GPC
Purity ≥99.9%
Appearance Colorless liquid
Molecular Formula C4H8O
Molecular Weight 72.11 g/mol
Boiling Point 66 °C
Melting Point -108 °C
Density 0.887 g/mL
Refractive Index n20/D 1.407
Flash Point -14 °F
Solubility Miscible with water, ethanol, diethyl ether
FAQ
What is Tetrahydrofuran (THF) commonly used for in the laboratory setting?
THF is commonly used as a solvent in various laboratory applications, including UV spectroscopy, IR spectroscopy, HPLC (High Performance Liquid Chromatography), and GPC (Gel Permeation Chromatography). It is known for its high solvency power and ability to dissolve a wide range of polar and non-polar compounds, making it a versatile choice for many different types of analyses and experiments.

Is Tetrahydrofuran (THF) suitable for use in UV spectroscopy?
Yes, THF is a commonly used solvent in UV spectroscopy due to its low UV absorption in the range of interest for many UV analytes. It is especially useful for UV-Vis spectrophotometry, where the solvent's absorbance can interfere with the measurement of the sample's absorbance. THF's low UV absorbance makes it an ideal choice for UV spectroscopy applications.

Can Tetrahydrofuran (THF) be used for Infrared (IR) spectroscopy?
Yes, THF is suitable for use in IR spectroscopy due to its ability to dissolve a wide range of organic and inorganic compounds without interfering with the IR spectra of the samples. Its low IR absorption in the relevant range allows for clear and accurate IR spectra to be obtained, making it a popular choice for many IR spectroscopy applications.

Is Tetrahydrofuran (THF) compatible with High Performance Liquid Chromatography (HPLC)?
Yes, THF is compatible with HPLC and is frequently used as a solvent in HPLC analyses. Its high solvency power and ability to dissolve a wide range of analytes make it a versatile choice for HPLC separations. THF can be used in both normal- and reverse-phase HPLC methods, offering flexibility in method development and optimization.

Can Tetrahydrofuran (THF) be used in Gel Permeation Chromatography (GPC)?
Yes, THF is commonly used in GPC as a solvent for the analysis of polymer samples. Its ability to dissolve a wide range of polymers and its compatibility with various GPC columns and detectors make it a popular choice for GPC analyses. THF can be used in both analytical and preparative GPC applications, providing accurate and reliable results for the characterization of polymer samples.
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