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Product Name | Silylation reagent HMDS pack of 6x50 mL |
Packaging | 6x50 mL bottles |
Reagent Type | Silylation reagent |
Quantity | 6 bottles of 50 mL each |
Package Size | 300 mL total |
Application | Silylation of compounds for analysis |
Product Code | HMDS-6x50 |
Storage Conditions | Store at room temperature |
Shelf Life | 2 years |
Manufacturer | Not specified |
Shipping Restrictions | May require special handling |
Hazards | Flammable liquid |
Recommended Usage | Follow manufacturer's instructions |
Compatible Instruments | GC-MS, NMR, IR spectroscopy |
Solubility | Soluble in organic solvents |
Appearance | Colorless liquid |
Odor | Characteristic odor |
Melting Point | Not applicable for liquid reagent |
Boiling Point | Not specified |
FAQ
What is HMDS and what is its function in silylation reactions?
HMDS stands for Hexamethyldisilazane, a commonly used silylation reagent in organic synthesis. Its primary function is to protect functional groups during reactions, particularly in gas chromatography and mass spectrometry analyses.
How is HMDS typically used in silylation reactions?
HMDS is typically added to a reaction mixture to silylate functional groups, such as hydroxyl groups. This introduces trimethylsilyl groups to the molecule, making it more volatile and less prone to unwanted reactions or degradation.
What are the advantages of using HMDS over other silylation reagents?
HMDS is preferred for silylation reactions due to its high reactivity, cost-effectiveness, and compatibility with a wide range of functional groups. It also produces trimethylsilyl derivatives that are easily detectable by analytical techniques.
Are there any safety precautions to consider when working with HMDS?
Yes, HMDS is a hazardous chemical that should be handled with caution. It is highly flammable and can cause skin and eye irritation upon contact. Proper personal protective equipment, such as gloves and goggles, should be worn when working with HMDS.
How can I store the pack of 6x50 mL HMDS reagent to ensure its longevity?
HMDS should be stored in a cool, dry place away from direct sunlight and sources of heat. It is recommended to keep the containers tightly closed when not in use to prevent contamination or evaporation of the reagent.
HMDS stands for Hexamethyldisilazane, a commonly used silylation reagent in organic synthesis. Its primary function is to protect functional groups during reactions, particularly in gas chromatography and mass spectrometry analyses.
How is HMDS typically used in silylation reactions?
HMDS is typically added to a reaction mixture to silylate functional groups, such as hydroxyl groups. This introduces trimethylsilyl groups to the molecule, making it more volatile and less prone to unwanted reactions or degradation.
What are the advantages of using HMDS over other silylation reagents?
HMDS is preferred for silylation reactions due to its high reactivity, cost-effectiveness, and compatibility with a wide range of functional groups. It also produces trimethylsilyl derivatives that are easily detectable by analytical techniques.
Are there any safety precautions to consider when working with HMDS?
Yes, HMDS is a hazardous chemical that should be handled with caution. It is highly flammable and can cause skin and eye irritation upon contact. Proper personal protective equipment, such as gloves and goggles, should be worn when working with HMDS.
How can I store the pack of 6x50 mL HMDS reagent to ensure its longevity?
HMDS should be stored in a cool, dry place away from direct sunlight and sources of heat. It is recommended to keep the containers tightly closed when not in use to prevent contamination or evaporation of the reagent.