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| Name | Bis-(trimethylsilyl)-trifluoroacetamide (Reag. Ph. Eur.) for GC |
| Cas Number | 25561-30-2 |
| Formula | C8H18F6Si2 |
| Molecular Weight | 302.41 g/mol |
| Appearance | Colorless liquid |
| Melting Point | -10°C |
| Boiling Point | 156-157°C |
| Density | 1.12 g/cm3 |
| Purity | ≥ 98% |
| Storage Conditions | Store in a cool, dry place |
| Solubility | Insoluble in water |
| Applications | Derivatization reagent for GC analysis |
FAQ
What is Bis-(trimethylsilyl)-trifluoroacetamide (Reag. Ph. Eur.) and how is it used in Gas
Chromatography (GC)?
Bis-(trimethylsilyl)-trifluoroacetamide (BSTFA) is a derivatization reagent commonly used in Gas Chromatography (GC) to enhance the detectability of compounds by converting them into more volatile and thermally stable forms, allowing for better separation and analysis of complex mixtures.
What are the key benefits of using Bis-(trimethylsilyl)-trifluoroacetamide (BSTFA) in GC?
BSTFA offers rapid derivatization, increased sensitivity, improved detection limits, enhanced peak shapes, and compatibility with a wide range of compounds, making it a versatile and effective tool for GC analysis.
How is Bis-(trimethylsilyl)-trifluoroacetamide (BSTFA) applied in GC sample preparation?
BSTFA is typically used to derivatize polar compounds with hydroxyl, carboxyl, or amino functional groups to enhance their volatilization and improve their chromatographic behavior. It can be added directly to the sample or used in conjunction with other reagents in a derivatization reaction prior to injection into the GC system.
What are some common applications of Bis-(trimethylsilyl)-trifluoroacetamide (BSTFA) in GC analysis?
BSTFA is widely used in the analysis of pharmaceuticals, environmental samples, food and beverages, forensic samples, and other complex matrices where derivatization is necessary to achieve accurate and reliable results. It is particularly useful for the analysis of polar compounds that are not well-suited for direct injection into the GC system.
Are there any special considerations to keep in mind when working with Bis-(trimethylsilyl)-trifluoroacetamide (BSTFA) in GC?
While BSTFA is a widely used derivatization reagent, it is important to ensure proper handling and storage to avoid contamination and degradation. Users should follow recommended protocols for sample preparation and derivatization to achieve optimal results in GC analysis.
Bis-(trimethylsilyl)-trifluoroacetamide (BSTFA) is a derivatization reagent commonly used in Gas Chromatography (GC) to enhance the detectability of compounds by converting them into more volatile and thermally stable forms, allowing for better separation and analysis of complex mixtures.
What are the key benefits of using Bis-(trimethylsilyl)-trifluoroacetamide (BSTFA) in GC?
BSTFA offers rapid derivatization, increased sensitivity, improved detection limits, enhanced peak shapes, and compatibility with a wide range of compounds, making it a versatile and effective tool for GC analysis.
How is Bis-(trimethylsilyl)-trifluoroacetamide (BSTFA) applied in GC sample preparation?
BSTFA is typically used to derivatize polar compounds with hydroxyl, carboxyl, or amino functional groups to enhance their volatilization and improve their chromatographic behavior. It can be added directly to the sample or used in conjunction with other reagents in a derivatization reaction prior to injection into the GC system.
What are some common applications of Bis-(trimethylsilyl)-trifluoroacetamide (BSTFA) in GC analysis?
BSTFA is widely used in the analysis of pharmaceuticals, environmental samples, food and beverages, forensic samples, and other complex matrices where derivatization is necessary to achieve accurate and reliable results. It is particularly useful for the analysis of polar compounds that are not well-suited for direct injection into the GC system.
Are there any special considerations to keep in mind when working with Bis-(trimethylsilyl)-trifluoroacetamide (BSTFA) in GC?
While BSTFA is a widely used derivatization reagent, it is important to ensure proper handling and storage to avoid contamination and degradation. Users should follow recommended protocols for sample preparation and derivatization to achieve optimal results in GC analysis.
