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Name | 1-Octane Sulfonic Acid Sodium Salt for HPLC |
Synonyms | Sodium octanesulfonate |
Molecular Formula | C8H17NaO3S |
Molecular Weight | 228.27 g/mol |
Appearance | White powder |
Solubility | Soluble in water |
Purity | ≥ 98% |
Storage Condition | Store at room temperature |
Applications | High-performance liquid chromatography (HPLC) |
Cas Number | 1984-06-1 |
Pubchem Cid | 23689311 |
FAQ
What is 1-Octane Sulfonic Acid Sodium Salt and how is it used in HPLC?
1-Octane Sulfonic Acid Sodium Salt is a commonly used ion-pairing reagent in high-performance liquid chromatography (HPLC) for the separation of various compounds. It helps to improve the retention and resolution of analytes by forming ion pairs with them, making it easier to detect and quantify specific compounds in a sample.
What are the benefits of using 1-Octane Sulfonic Acid Sodium Salt in HPLC?
Some benefits of using 1-Octane Sulfonic Acid Sodium Salt in HPLC include:
- Improved retention and separation of analytes
- Enhanced sensitivity and detection of compounds
- Increased resolution of peaks in chromatograms
- Compatibility with various types of chromatographic columns
- Cost-effective alternative to other ion-pairing reagents
How should 1-Octane Sulfonic Acid Sodium Salt be stored and handled for optimal performance?
1-Octane Sulfonic Acid Sodium Salt should be stored in a cool, dry place away from direct sunlight and moisture to prevent degradation. It is important to handle the reagent with care and use proper personal protective equipment, such as gloves and goggles, to avoid contact with skin or eyes. Additionally, make sure to follow the manufacturer's instructions for the correct concentration and preparation of solutions for HPLC analysis.
Are there any specific applications or types of compounds that are best suited for 1-Octane Sulfonic Acid Sodium Salt in HPLC?
1-Octane Sulfonic Acid Sodium Salt is commonly used for the analysis of polar and ionizable compounds, such as organic acids, pharmaceuticals, amino acids, and peptides. It is particularly effective for the separation of acidic or basic compounds that require ion-pairing reagents to facilitate their retention and detection in HPLC. Researchers and chromatographers can experiment with different concentrations and conditions to optimize the performance of 1-Octane Sulfonic Acid Sodium Salt for specific applications.
Can 1-Octane Sulfonic Acid Sodium Salt be used in combination with other reagents or additives in HPLC methods?
Yes, 1-Octane Sulfonic Acid Sodium Salt can be used in combination with other ion-pairing reagents, buffers, and modifiers to enhance the selectivity and efficiency of HPLC methods. By optimizing the mobile phase composition and pH conditions, chromatographers can achieve better separation of complex mixtures and improve the overall performance of their analytical methods. It is important to validate the compatibility and efficacy of different reagents when developing new HPLC methods with 1-Octane Sulfonic Acid Sodium Salt.
1-Octane Sulfonic Acid Sodium Salt is a commonly used ion-pairing reagent in high-performance liquid chromatography (HPLC) for the separation of various compounds. It helps to improve the retention and resolution of analytes by forming ion pairs with them, making it easier to detect and quantify specific compounds in a sample.
What are the benefits of using 1-Octane Sulfonic Acid Sodium Salt in HPLC?
Some benefits of using 1-Octane Sulfonic Acid Sodium Salt in HPLC include:
- Improved retention and separation of analytes
- Enhanced sensitivity and detection of compounds
- Increased resolution of peaks in chromatograms
- Compatibility with various types of chromatographic columns
- Cost-effective alternative to other ion-pairing reagents
How should 1-Octane Sulfonic Acid Sodium Salt be stored and handled for optimal performance?
1-Octane Sulfonic Acid Sodium Salt should be stored in a cool, dry place away from direct sunlight and moisture to prevent degradation. It is important to handle the reagent with care and use proper personal protective equipment, such as gloves and goggles, to avoid contact with skin or eyes. Additionally, make sure to follow the manufacturer's instructions for the correct concentration and preparation of solutions for HPLC analysis.
Are there any specific applications or types of compounds that are best suited for 1-Octane Sulfonic Acid Sodium Salt in HPLC?
1-Octane Sulfonic Acid Sodium Salt is commonly used for the analysis of polar and ionizable compounds, such as organic acids, pharmaceuticals, amino acids, and peptides. It is particularly effective for the separation of acidic or basic compounds that require ion-pairing reagents to facilitate their retention and detection in HPLC. Researchers and chromatographers can experiment with different concentrations and conditions to optimize the performance of 1-Octane Sulfonic Acid Sodium Salt for specific applications.
Can 1-Octane Sulfonic Acid Sodium Salt be used in combination with other reagents or additives in HPLC methods?
Yes, 1-Octane Sulfonic Acid Sodium Salt can be used in combination with other ion-pairing reagents, buffers, and modifiers to enhance the selectivity and efficiency of HPLC methods. By optimizing the mobile phase composition and pH conditions, chromatographers can achieve better separation of complex mixtures and improve the overall performance of their analytical methods. It is important to validate the compatibility and efficacy of different reagents when developing new HPLC methods with 1-Octane Sulfonic Acid Sodium Salt.