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| Name | 1-Pentane Sulfonic Acid Sodium Salt for HPLC |
| Cas Number | 28363-41-7 |
| Molecular Formula | C5H11NaO3S |
| Molecular Weight | 174.19 g/mol |
| Appearance | White to off-white crystalline powder |
| Solubility | Soluble in water and most organic solvents |
| Purity | ≥ 99% |
| Storage Condition | Store at room temperature |
| Usage | Commonly used as an ion-pairing reagent in HPLC |
| Application | Analytical chemistry, chromatography |
| Melting Point | 142-144°C |
| Boiling Point | Not available |
FAQ
What is 1-Pentane Sulfonic Acid Sodium Salt and how is it used in HPLC?
1-Pentane Sulfonic Acid Sodium Salt is a high purity buffer salt used for ion-pairing chromatography in HPLC. It is commonly used in the analysis of polar compounds by reverse phase HPLC. This compound helps improve the resolution and retention of certain analytes, especially those with limited solubility in water.
Why is 1-Pentane Sulfonic Acid Sodium Salt preferred for HPLC applications?
1-Pentane Sulfonic Acid Sodium Salt is preferred for HPLC applications due to its compatibility with various detector types and its ability to provide sharp and well-defined peaks. It is also known for its low UV absorbance, making it suitable for use in UV detection methods commonly employed in HPLC analysis. Additionally, this compound offers good stability and reproducibility in HPLC separations.
What are the advantages of using 1-Pentane Sulfonic Acid Sodium Salt in HPLC?
The advantages of using 1-Pentane Sulfonic Acid Sodium Salt in HPLC include improved peak shape, enhanced selectivity, and increased resolution of analytes. It also aids in the analysis of polar compounds by forming strong ion pairs with them, which facilitates their retention on the column. This compound is easy to use and can be quickly dissolved in aqueous solvents, making it a convenient choice for HPLC applications.
Can 1-Pentane Sulfonic Acid Sodium Salt be used in combination with other buffers or additives in HPLC?
Yes, 1-Pentane Sulfonic Acid Sodium Salt can be used in combination with other buffers or additives in HPLC to achieve specific separation goals. By adjusting the concentration and composition of the mobile phase, researchers can fine-tune the chromatographic conditions to optimize separation of analytes. Additionally, this compound is compatible with various stationary phases and can be used in gradient elution methods to improve separation efficiency.
How can I store and handle 1-Pentane Sulfonic Acid Sodium Salt for HPLC purposes?
1-Pentane Sulfonic Acid Sodium Salt should be stored in a cool, dry place away from direct sunlight and moisture. It is important to handle this compound with care and use appropriate protective equipment, such as gloves and goggles, when working with it. When preparing solutions for HPLC analysis, make sure to accurately weigh the required amount of 1-Pentane Sulfonic Acid Sodium Salt and dissolve it in the desired solvent following recommended procedures.
1-Pentane Sulfonic Acid Sodium Salt is a high purity buffer salt used for ion-pairing chromatography in HPLC. It is commonly used in the analysis of polar compounds by reverse phase HPLC. This compound helps improve the resolution and retention of certain analytes, especially those with limited solubility in water.
Why is 1-Pentane Sulfonic Acid Sodium Salt preferred for HPLC applications?
1-Pentane Sulfonic Acid Sodium Salt is preferred for HPLC applications due to its compatibility with various detector types and its ability to provide sharp and well-defined peaks. It is also known for its low UV absorbance, making it suitable for use in UV detection methods commonly employed in HPLC analysis. Additionally, this compound offers good stability and reproducibility in HPLC separations.
What are the advantages of using 1-Pentane Sulfonic Acid Sodium Salt in HPLC?
The advantages of using 1-Pentane Sulfonic Acid Sodium Salt in HPLC include improved peak shape, enhanced selectivity, and increased resolution of analytes. It also aids in the analysis of polar compounds by forming strong ion pairs with them, which facilitates their retention on the column. This compound is easy to use and can be quickly dissolved in aqueous solvents, making it a convenient choice for HPLC applications.
Can 1-Pentane Sulfonic Acid Sodium Salt be used in combination with other buffers or additives in HPLC?
Yes, 1-Pentane Sulfonic Acid Sodium Salt can be used in combination with other buffers or additives in HPLC to achieve specific separation goals. By adjusting the concentration and composition of the mobile phase, researchers can fine-tune the chromatographic conditions to optimize separation of analytes. Additionally, this compound is compatible with various stationary phases and can be used in gradient elution methods to improve separation efficiency.
How can I store and handle 1-Pentane Sulfonic Acid Sodium Salt for HPLC purposes?
1-Pentane Sulfonic Acid Sodium Salt should be stored in a cool, dry place away from direct sunlight and moisture. It is important to handle this compound with care and use appropriate protective equipment, such as gloves and goggles, when working with it. When preparing solutions for HPLC analysis, make sure to accurately weigh the required amount of 1-Pentane Sulfonic Acid Sodium Salt and dissolve it in the desired solvent following recommended procedures.
