D-Luciferin Sodium Salt

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Name D-Luciferin Sodium Salt
CAS Number 103404-75-7
Formula C11H7O3SNa
Molar Mass 250.23 g/mol
Appearance White to off-white powder
Solubility Soluble in water
Storage Store at -20°C
PH Range 7-9
Usage Bioluminescence assays
Purity ≥98%
Melting Point 174-176°C
Stability Stable under recommended storage conditions
Odor Odorless
Density 1.48 g/cm3
PubChem CID 136434676
Boiling Point Not available
Flash Point Not applicable
Risk Phrases Not applicable
Safety Phrases S24/25 - Avoid contact with skin and eyes
FAQ
What is D-Luciferin Sodium Salt and how is it used in research applications?
D-Luciferin Sodium Salt is a substrate used for bioluminescence imaging in various research applications. It is commonly used in combination with luciferase enzymes to produce light signals that are then detected and measured. This reagent is essential for studies involving gene expression, protein dynamics, and cell tracking.

What are the advantages of using D-Luciferin Sodium Salt over other substrates?
One of the main advantages of using D-Luciferin Sodium Salt is its high sensitivity, which allows for the detection of low levels of luciferase activity. Additionally, this substrate has a low background signal, which helps to improve signal-to-noise ratios in bioluminescence imaging experiments. It is also stable and easily penetrates cell membranes, making it an ideal choice for in vivo studies.

How is D-Luciferin Sodium Salt typically administered in research experiments?
D-Luciferin Sodium Salt is typically administered to cells or animals via injection, either intravenously or intraperitoneally, depending on the specific experimental requirements. The substrate is rapidly taken up by cells and tissues, where it interacts with luciferase enzymes to produce bioluminescent signals. Researchers can then visualize and quantify these signals using specialized imaging systems.

What are some common applications of D-Luciferin Sodium Salt in biomedical research?
D-Luciferin Sodium Salt is widely used in biomedical research for a variety of applications, including monitoring gene expression, studying protein-protein interactions, tracking cell migration, and evaluating drug efficacy. Researchers can use this substrate to non-invasively monitor biological processes in real time, both in cell culture and in live animal models. Its versatility and sensitivity make it a valuable tool for a wide range of studies.

Are there any specific precautions or storage recommendations for working with D-Luciferin Sodium Salt?
When working with D-Luciferin Sodium Salt, it is important to handle the substrate with care to avoid contamination and degradation. Store it in a cool, dry place away from light and moisture, and avoid repeated freeze-thaw cycles. Follow manufacturer's recommendations for handling, preparation, and disposal of the substrate to ensure accurate and reliable results in your research experiments.
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