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| Product Name | Acetonitrile for LC-MS |
| Cas Number | 75-05-8 |
| Molecular Formula | C2H3N |
| Molecular Weight | 41.05 g/mol |
| Appearance | Clear, colorless liquid |
| Solubility | Miscible in water |
| Purity | ≥ 99.9% |
| Boiling Point | 81-83°C |
| Density | 0.786 g/mL at 25°C |
| Flash Point | -2°C |
| Storage Condition | Store at room temperature in a tightly closed container |
FAQ
What is acetonitrile and how is it used in LC-MS analysis?
Acetonitrile, often referred to as MeCN, is a common solvent used in liquid chromatography-mass spectrometry (LC-MS) analysis. It is widely used due to its excellent solubility, volatility, and compatibility with a wide range of analytes. Acetonitrile is commonly used as a mobile phase solvent in LC-MS to separate compounds of interest before entering the mass spectrometer for detection and analysis.
Why is acetonitrile preferred over other solvents for LC-MS applications?
Acetonitrile is preferred over other solvents in LC-MS applications due to its low UV cutoff, which allows for more sensitive detection of analytes. Additionally, acetonitrile has a low viscosity, which promotes better chromatographic efficiency and faster analysis times. Its compatibility with a wide range of compounds also makes it a versatile choice for LC-MS applications.
What are the key advantages of using acetonitrile for LC-MS analysis?
The key advantages of using acetonitrile for LC-MS analysis include its excellent solubility, low UV cutoff, low viscosity, and compatibility with a wide range of analytes. These features make acetonitrile a popular choice for liquid chromatography-mass spectrometry applications, as they promote sensitive detection, efficient separation, and versatile analysis capabilities.
Are there any limitations or considerations to keep in mind when using acetonitrile in LC-MS analysis?
While acetonitrile is a widely used solvent in LC-MS analysis, there are some limitations and considerations to keep in mind. Acetonitrile can be more expensive than other solvents, so cost considerations may come into play when choosing a solvent for LC-MS analysis. Additionally, acetonitrile is volatile and flammable, so proper safety precautions should be taken when handling and storing the solvent.
Can acetonitrile be used in combination with other solvents in LC-MS analysis?
Yes, acetonitrile can be used in combination with other solvents in LC-MS analysis to optimize separation and detection of analytes. By adjusting the composition of the mobile phase, analysts can tailor the chromatographic conditions to meet the specific needs of their analytical method. Acetonitrile is often used in combination with water or other organic solvents to achieve the desired chromatographic performance in LC-MS analysis.
Acetonitrile, often referred to as MeCN, is a common solvent used in liquid chromatography-mass spectrometry (LC-MS) analysis. It is widely used due to its excellent solubility, volatility, and compatibility with a wide range of analytes. Acetonitrile is commonly used as a mobile phase solvent in LC-MS to separate compounds of interest before entering the mass spectrometer for detection and analysis.
Why is acetonitrile preferred over other solvents for LC-MS applications?
Acetonitrile is preferred over other solvents in LC-MS applications due to its low UV cutoff, which allows for more sensitive detection of analytes. Additionally, acetonitrile has a low viscosity, which promotes better chromatographic efficiency and faster analysis times. Its compatibility with a wide range of compounds also makes it a versatile choice for LC-MS applications.
What are the key advantages of using acetonitrile for LC-MS analysis?
The key advantages of using acetonitrile for LC-MS analysis include its excellent solubility, low UV cutoff, low viscosity, and compatibility with a wide range of analytes. These features make acetonitrile a popular choice for liquid chromatography-mass spectrometry applications, as they promote sensitive detection, efficient separation, and versatile analysis capabilities.
Are there any limitations or considerations to keep in mind when using acetonitrile in LC-MS analysis?
While acetonitrile is a widely used solvent in LC-MS analysis, there are some limitations and considerations to keep in mind. Acetonitrile can be more expensive than other solvents, so cost considerations may come into play when choosing a solvent for LC-MS analysis. Additionally, acetonitrile is volatile and flammable, so proper safety precautions should be taken when handling and storing the solvent.
Can acetonitrile be used in combination with other solvents in LC-MS analysis?
Yes, acetonitrile can be used in combination with other solvents in LC-MS analysis to optimize separation and detection of analytes. By adjusting the composition of the mobile phase, analysts can tailor the chromatographic conditions to meet the specific needs of their analytical method. Acetonitrile is often used in combination with water or other organic solvents to achieve the desired chromatographic performance in LC-MS analysis.
