Dimethyl Sulfoxide for UV, IR, HPLC, GPC

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Product Name Dimethyl Sulfoxide for UV, IR, HPLC, GPC
CAS Number 67-68-5
Molecular Formula C2H6OS
Molecular Weight 78.13 g/mol
Appearance Colorless liquid
Purity 99.9%
Solubility Miscible in water and most organic solvents
Boiling Point 189°C
Flash Point 89°C
Density 1.10 g/cm3
Applications Used as a solvent, cryoprotectant, and in pharmaceutical formulations
FAQ
What is Dimethyl Sulfoxide (DMSO) and what are its applications in UV, IR, HPLC, and GPC?

Dimethyl Sulfoxide (DMSO) is a highly versatile solvent that is commonly used in various applications such as UV (Ultraviolet) spectroscopy, IR (Infrared) spectroscopy, HPLC (High Performance Liquid Chromatography), and GPC (Gel Permeation Chromatography). It is known for its ability to dissolve a wide range of organic and inorganic compounds, making it an essential component in many laboratory settings. DMSO is also valued for its high solubility in water and its ability to penetrate biological membranes, which makes it a valuable tool in the field of biochemistry and cell biology.

How does Dimethyl Sulfoxide (DMSO) function in UV spectroscopy?

In UV spectroscopy, Dimethyl Sulfoxide (DMSO) is often used as a solvent for analyzing the absorption of ultraviolet light by various compounds. DMSO has a broad spectral range that extends from the ultraviolet to the visible region, making it suitable for a wide range of applications. Additionally, DMSO has low UV absorption itself, which makes it an ideal solvent for UV spectroscopy as it does not interfere with the absorption spectra of the compounds being analyzed. Its high solubility and stability also make DMSO a preferred solvent for UV spectroscopy experiments.

What role does Dimethyl Sulfoxide (DMSO) play in IR spectroscopy?

In IR spectroscopy, Dimethyl Sulfoxide (DMSO) serves as a solvent for analyzing the infrared absorption and vibration frequencies of various compounds. DMSO is compatible with a wide range of sample types and has good solubility for many organic and inorganic compounds, making it a versatile solvent for IR spectroscopy experiments. Furthermore, DMSO itself has relatively weak absorption in the infrared region, allowing for accurate analysis of the absorption spectra of the compounds under investigation. This makes DMSO an excellent choice for IR spectroscopy applications.

How is Dimethyl Sulfoxide (DMSO) utilized in HPLC (High Performance Liquid Chromatography)?

Dimethyl Sulfoxide (DMSO) is frequently employed as a solvent in HPLC (High Performance Liquid Chromatography) due to its exceptional solvating properties and compatibility with a wide range of analytes. DMSO is known for its ability to dissolve both polar and non-polar compounds, making it a versatile solvent for HPLC separations. Its high solubility and low UV absorbance also ensure that DMSO does not interfere with the detection of analytes during the HPLC process. As a result, DMSO is commonly used in HPLC to achieve efficient and reliable separations of complex mixtures.

What advantages does Dimethyl Sulfoxide (DMSO) offer in GPC (Gel Permeation Chromatography)?

In GPC (Gel Permeation Chromatography), Dimethyl Sulfoxide (DMSO) is often utilized as a solvent for analyzing the molecular weight distribution of polymers and other macromolecules. DMSO has excellent solvating properties for a wide range of polymers, ensuring accurate and reproducible results in GPC experiments. Its high solubility and low viscosity make DMSO an ideal solvent for GPC, allowing for efficient separations and precise determination of molecular weight distributions. Additionally, DMSO's compatibility with various detector systems in GPC further enhances its utility in polymer analysis.
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