N,N-Dimethylacetamide for UV, IR, HPLC

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Name N,N-Dimethylacetamide
Product Type UV, IR, HPLC
CAS Number 127-19-5
Molecular Formula C4H9NO
Molar Mass 87.12 g/mol
Appearance Colorless liquid
Density 0.937 g/cm3
Boiling Point 164-166°C
Melting Point -20°C
Solubility Miscible in water, ethanol, ether
Flash Point 66°C
Refractive Index n20/D 1.437 (lit.)
Purity 99%
Storage Store in a cool, dry, well-ventilated area
Usage Commonly used as a solvent in various chemical processes
Hazards May cause skin and eye irritation, harmful if swallowed or inhaled
FAQ
What is N,N-Dimethylacetamide (DMAc) and how is it used in UV, IR, and HPLC applications?
N,N-Dimethylacetamide (DMAc) is a versatile solvent that is commonly used in various analytical techniques such as Ultraviolet (UV) spectroscopy, Infrared (IR) spectroscopy, and High-Performance Liquid Chromatography (HPLC). It is a colorless liquid with a high boiling point and low viscosity, making it ideal for these applications. DMAc is known for its ability to dissolve a wide range of compounds, making it a popular choice in analytical laboratories.

How does N,N-Dimethylacetamide (DMAc) perform in UV spectroscopy?
In UV spectroscopy, DMAc is used as a solvent to dissolve samples for analysis. It has a wide spectral range and low UV absorption, making it suitable for UV measurements. DMAc is also known for its stability and compatibility with a variety of UV-active compounds, making it a reliable choice for UV spectroscopy applications.

What are the advantages of using N,N-Dimethylacetamide (DMAc) in IR spectroscopy?
In IR spectroscopy, DMAc is utilized as a solvent to dissolve samples for analysis. DMAc has a low UV cut-off, which allows it to be used in IR measurements without interfering with the spectral data. It also has good solubility for a wide range of compounds, making it a versatile solvent for IR spectroscopy applications.

How is N,N-Dimethylacetamide (DMAc) beneficial for High-Performance Liquid Chromatography (HPLC)?
In HPLC, DMAc is commonly used as a solvent due to its high solvating power and compatibility with a variety of compounds. DMAc can be used to dissolve both polar and non-polar compounds, making it a versatile choice for HPLC applications. Its low viscosity and high boiling point also contribute to its performance in HPLC systems, providing reliable and consistent results.

What safety precautions should be taken when handling N,N-Dimethylacetamide (DMAc) in analytical applications?
When handling DMAc in analytical applications, it is important to take appropriate safety precautions due to its potential health hazards. DMAc is a skin and eye irritant, and prolonged or repeated exposure should be avoided. It is also flammable and should be stored and handled in a well-ventilated area away from sources of ignition. Personal protective equipment, such as gloves and goggles, should be worn when working with DMAc to minimize the risk of exposure.
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