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| Name | Tetrachloroethylene for UV, IR, HPLC, GPC |
| Formula | C2Cl4 |
| Molar Mass | 165.83 g/mol |
| Appearance | Colorless liquid |
| Density | 1.622 g/cm3 |
| Melting Point | -22.4 °C |
| Boiling Point | 121.1 °C |
| Solubility | 0.15 g/L in water |
| Purity | ≥ 99% |
| Storage Condition | Store in a cool, dry, well-ventilated area |
| Applications | Used as a solvent in dry cleaning, metal degreasing, and in the manufacturing of other chemicals |
FAQ
What is tetrachloroethylene and how is it used in UV, IR, HPLC, and GPC
applications?
Tetrachloroethylene, also known as perchloroethylene, is a colorless liquid used in various applications such as UV spectrophotometry, IR spectroscopy, HPLC (High Performance Liquid Chromatography), and GPC (Gel Permeation Chromatography). In these applications, it is utilized as a solvent due to its excellent properties such as high stability, low reactivity, and good solubility for a wide range of compounds.
What are the specific benefits of using tetrachloroethylene in UV and IR applications?
Tetrachloroethylene is commonly used in UV and IR applications as a solvent due to its high transmittance in the UV region and low water absorption in the IR region. This makes it an ideal choice for spectroscopic analysis, as it provides clear and accurate results without interference from impurities or contaminants. Additionally, tetrachloroethylene has a low boiling point, which allows for easy evaporation after analysis, further ensuring the purity of the samples.
How does tetrachloroethylene perform in HPLC applications compared to other solvents?
In HPLC applications, the choice of solvent is crucial to achieving accurate and reproducible results. Tetrachloroethylene is a popular choice due to its low viscosity, high density, and low UV absorbance, which make it suitable for separating a wide range of compounds with different polarities. It also provides excellent peak shapes and resolution, leading to high-quality chromatograms that are easy to interpret and analyze. Overall, tetrachloroethylene is a reliable solvent for HPLC applications that can help improve the efficiency and accuracy of your analyses.
What are the advantages of using tetrachloroethylene in GPC applications?
GPC is a technique used for determining the molecular weight distribution of polymers and other macromolecules. Tetrachloroethylene is a common choice of eluent in GPC due to its compatibility with a wide range of polymers, including polystyrene, poly(methyl methacrylate), and polyethylene glycol. It offers good solubility for these polymers, allowing for accurate and reproducible results. Additionally, tetrachloroethylene has a low UV absorbance and low refractive index increment, making it an ideal solvent for GPC analyses where precise measurements are essential.
Are there any safety considerations when working with tetrachloroethylene in laboratory settings?
Tetrachloroethylene should be handled with care in laboratory settings, as it is a toxic and potentially carcinogenic compound. It should only be used in well-ventilated areas, and personal protective equipment such as gloves, goggles, and lab coats should be worn to minimize exposure. Additionally, tetrachloroethylene should be stored in a cool, dry place away from heat sources and incompatible materials. Proper disposal methods should be followed to prevent environmental contamination. It is important to review the safety data sheet provided by the manufacturer for specific guidelines on handling, storage, and disposal of tetrachloroethylene.
Tetrachloroethylene, also known as perchloroethylene, is a colorless liquid used in various applications such as UV spectrophotometry, IR spectroscopy, HPLC (High Performance Liquid Chromatography), and GPC (Gel Permeation Chromatography). In these applications, it is utilized as a solvent due to its excellent properties such as high stability, low reactivity, and good solubility for a wide range of compounds.
What are the specific benefits of using tetrachloroethylene in UV and IR applications?
Tetrachloroethylene is commonly used in UV and IR applications as a solvent due to its high transmittance in the UV region and low water absorption in the IR region. This makes it an ideal choice for spectroscopic analysis, as it provides clear and accurate results without interference from impurities or contaminants. Additionally, tetrachloroethylene has a low boiling point, which allows for easy evaporation after analysis, further ensuring the purity of the samples.
How does tetrachloroethylene perform in HPLC applications compared to other solvents?
In HPLC applications, the choice of solvent is crucial to achieving accurate and reproducible results. Tetrachloroethylene is a popular choice due to its low viscosity, high density, and low UV absorbance, which make it suitable for separating a wide range of compounds with different polarities. It also provides excellent peak shapes and resolution, leading to high-quality chromatograms that are easy to interpret and analyze. Overall, tetrachloroethylene is a reliable solvent for HPLC applications that can help improve the efficiency and accuracy of your analyses.
What are the advantages of using tetrachloroethylene in GPC applications?
GPC is a technique used for determining the molecular weight distribution of polymers and other macromolecules. Tetrachloroethylene is a common choice of eluent in GPC due to its compatibility with a wide range of polymers, including polystyrene, poly(methyl methacrylate), and polyethylene glycol. It offers good solubility for these polymers, allowing for accurate and reproducible results. Additionally, tetrachloroethylene has a low UV absorbance and low refractive index increment, making it an ideal solvent for GPC analyses where precise measurements are essential.
Are there any safety considerations when working with tetrachloroethylene in laboratory settings?
Tetrachloroethylene should be handled with care in laboratory settings, as it is a toxic and potentially carcinogenic compound. It should only be used in well-ventilated areas, and personal protective equipment such as gloves, goggles, and lab coats should be worn to minimize exposure. Additionally, tetrachloroethylene should be stored in a cool, dry place away from heat sources and incompatible materials. Proper disposal methods should be followed to prevent environmental contamination. It is important to review the safety data sheet provided by the manufacturer for specific guidelines on handling, storage, and disposal of tetrachloroethylene.
