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| Name | Tetrahydrofuran |
| Type | Solvent |
| Purity | UV, IR, HPLC, GPC grade |
| Cas Number | 109-99-9 |
| Molecular Formula | C4H8O |
| Molecular Weight | 72.11 g/mol |
| Boiling Point | 66 °C |
| Melting Point | -108.5 °C |
| Density | 0.89 g/mL at 25 °C |
| Solubility | Miscible with water, ethanol, ether |
| Appearance | Clear, colorless liquid |
| Odor | Ether-like odor |
| Flash Point | -14 °C |
| Storage Condition | Store in a cool, dry place away from heat and flame |
| Applications | Used as a solvent in various chemical reactions and processes |
| Manufacturer | Multiple manufacturers worldwide |
FAQ
What is Tetrahydrofuran (THF) and what are its primary uses in UV, IR, HPLC, and GPC
analysis?
Tetrahydrofuran, commonly known as THF, is a versatile organic compound with the chemical formula (CH2)4O. It is a colorless, water-miscible liquid with a pleasant odor. THF is widely used as a solvent in various analytical techniques such as UV (ultraviolet) and IR (infrared) spectroscopy, HPLC (high-performance liquid chromatography), and GPC (gel permeation chromatography).
What are the benefits of using Tetrahydrofuran for UV analysis?
THF is commonly used as a solvent in UV spectroscopy due to its high solubility for a wide range of organic compounds. It has a low UV cutoff, making it ideal for analyzing compounds that absorb light in the UV range. Additionally, THF has low viscosity and high volatility, which makes it suitable for rapid and efficient UV analysis.
How is Tetrahydrofuran utilized in IR spectroscopy?
In IR spectroscopy, Tetrahydrofuran serves as a suitable solvent for preparing samples for analysis. It is commonly used to dissolve organic compounds that are being tested in the IR spectrometer. THF's ability to dissolve a variety of organic materials and its low interference with IR absorption make it an excellent choice for sample preparation in IR spectroscopy.
What role does Tetrahydrofuran play in HPLC analysis?
Tetrahydrofuran is frequently employed as a mobile phase solvent in HPLC analysis to separate and quantify compounds in a mixture. It is compatible with a wide range of detectors commonly used in HPLC, such as UV and mass spectrometry detectors. THF's high solvating power, low viscosity, and compatibility with various stationary phases make it an excellent choice for HPLC separations.
How does Tetrahydrofuran contribute to GPC analysis?
In GPC analysis, also known as size exclusion chromatography, Tetrahydrofuran is used as a mobile phase solvent to separate macromolecules based on their size. THF's excellent solvating properties and compatibility with a wide range of polymer samples make it an ideal choice for GPC applications. It helps achieve accurate and reproducible results by facilitating efficient separation of polymer samples based on their molecular weight.
In conclusion, Tetrahydrofuran (THF) is a versatile solvent widely used in various analytical techniques such as UV, IR, HPLC, and GPC analysis. Its high solvating power, compatibility with a wide range of organic compounds, and low interference with analytical instruments make it an indispensable solvent for researchers and analysts in the field of analytical chemistry.
Tetrahydrofuran, commonly known as THF, is a versatile organic compound with the chemical formula (CH2)4O. It is a colorless, water-miscible liquid with a pleasant odor. THF is widely used as a solvent in various analytical techniques such as UV (ultraviolet) and IR (infrared) spectroscopy, HPLC (high-performance liquid chromatography), and GPC (gel permeation chromatography).
What are the benefits of using Tetrahydrofuran for UV analysis?
THF is commonly used as a solvent in UV spectroscopy due to its high solubility for a wide range of organic compounds. It has a low UV cutoff, making it ideal for analyzing compounds that absorb light in the UV range. Additionally, THF has low viscosity and high volatility, which makes it suitable for rapid and efficient UV analysis.
How is Tetrahydrofuran utilized in IR spectroscopy?
In IR spectroscopy, Tetrahydrofuran serves as a suitable solvent for preparing samples for analysis. It is commonly used to dissolve organic compounds that are being tested in the IR spectrometer. THF's ability to dissolve a variety of organic materials and its low interference with IR absorption make it an excellent choice for sample preparation in IR spectroscopy.
What role does Tetrahydrofuran play in HPLC analysis?
Tetrahydrofuran is frequently employed as a mobile phase solvent in HPLC analysis to separate and quantify compounds in a mixture. It is compatible with a wide range of detectors commonly used in HPLC, such as UV and mass spectrometry detectors. THF's high solvating power, low viscosity, and compatibility with various stationary phases make it an excellent choice for HPLC separations.
How does Tetrahydrofuran contribute to GPC analysis?
In GPC analysis, also known as size exclusion chromatography, Tetrahydrofuran is used as a mobile phase solvent to separate macromolecules based on their size. THF's excellent solvating properties and compatibility with a wide range of polymer samples make it an ideal choice for GPC applications. It helps achieve accurate and reproducible results by facilitating efficient separation of polymer samples based on their molecular weight.
In conclusion, Tetrahydrofuran (THF) is a versatile solvent widely used in various analytical techniques such as UV, IR, HPLC, and GPC analysis. Its high solvating power, compatibility with a wide range of organic compounds, and low interference with analytical instruments make it an indispensable solvent for researchers and analysts in the field of analytical chemistry.
