Rifampicin

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Brand Name Rifampicin
Generic Name Rifampicin
Drug Class Antibiotic
Mechanism Of Action Inhibits bacterial RNA synthesis by binding to the beta-subunit of bacterial DNA-dependent RNA polymerase
Route Of Administration Oral, intravenous
Dosage Form Capsule, injection
Available Strengths 150mg, 300mg
Common Indications Tuberculosis, leprosy, meningococcal carriers
Contraindications Hypersensitivity to rifampicin, liver disease
Common Side Effects Nausea, vomiting, abdominal pain, rash
Pregnancy Category Category C
FAQ
What is Rifampicin and how does it work in the body?
Rifampicin is an antibiotic drug that is commonly used to treat bacterial infections. It works by inhibiting the activity of an enzyme called RNA polymerase, which is essential for the replication and transcription of bacterial DNA. By targeting this enzyme, Rifampicin is able to effectively kill off the bacteria causing the infection.

What conditions can Rifampicin be used to treat?
Rifampicin is commonly used to treat a variety of bacterial infections, including tuberculosis, leprosy, and certain types of meningitis. It is also sometimes used in combination with other antibiotics to treat infections that are resistant to other types of antibiotics.

How is Rifampicin typically taken?
Rifampicin is usually taken orally, in the form of a capsule or tablet. It is important to take Rifampicin exactly as prescribed by your healthcare provider, and to finish the entire course of treatment even if you start to feel better before the medication is gone. This will help to prevent the development of antibiotic resistance.

What are the potential side effects of Rifampicin?
Like all medications, Rifampicin can cause side effects in some people. Common side effects may include upset stomach, diarrhea, and changes in the color of your urine, sweat, or tears. More serious side effects are rare but can include liver damage, allergic reactions, and flu-like symptoms. If you experience any worrisome side effects while taking Rifampicin, be sure to contact your healthcare provider right away.

Are there any medications or substances that should be avoided while taking Rifampicin?
Yes, there are certain medications and substances that can interact negatively with Rifampicin. It is important to inform your healthcare provider of all the medications, supplements, and herbal products you are taking before starting treatment with Rifampicin. Some substances that may interact with Rifampicin include birth control pills, blood thinners, and certain anti-seizure medications. Your healthcare provider can help you navigate these potential interactions and make any necessary adjustments to your treatment plan.
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