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Product Name | n-Decyl-β-D-Maltoside |
Chemical Formula | C22H44O11 |
Molecular Weight | 516.59 g/mol |
Appearance | White to off-white solid |
Solubility | Soluble in water |
Purity | ≥99% |
Storage Condition | Store at room temperature |
Application | Crystallography studies |
Supplier | Commercial supplier |
Usage | Detergent for membrane protein solubilization |
Availability | Available for purchase |
Risk And Safety | Handle with gloves and goggles |
FAQ
What is n-Decyl-ß-D-Maltoside and how is it used in
crystallography?
n-Decyl-ß-D-Maltoside, also known as DM, is a non-ionic detergent commonly used in crystallography to solubilize and stabilize membrane proteins for structural studies. It is particularly effective in extracting membrane proteins from lipid bilayers while maintaining their native structure and functionality.
Why is n-Decyl-ß-D-Maltoside preferred over other detergents for crystallography applications?
DM is preferred over other detergents for crystallography applications due to its mild and non-denaturing properties. It has a low critical micelle concentration, which means that it forms micelles at lower concentrations compared to other detergents, making it ideal for solubilizing membrane proteins without causing damage to their structure.
How does n-Decyl-ß-D-Maltoside help in crystallography experiments?
n-Decyl-ß-D-Maltoside plays a crucial role in crystallography experiments by effectively extracting membrane proteins from lipid bilayers, solubilizing them in a detergent micelle, and stabilizing their native structure. This allows for the purification and crystallization of membrane proteins for X-ray crystallography studies, ultimately leading to the determination of their three-dimensional structures.
What are the key advantages of using n-Decyl-ß-D-Maltoside in crystallography?
The key advantages of using n-Decyl-ß-D-Maltoside in crystallography include its non-denaturing properties, ability to solubilize membrane proteins effectively, low critical micelle concentration, and compatibility with various membrane protein systems. Additionally, DM is known for its stability and consistency, making it a reliable choice for researchers working on structural biology studies.
In summary, n-Decyl-ß-D-Maltoside is a versatile and effective detergent for crystallography applications, offering researchers a powerful tool for studying membrane proteins and unraveling their structures through X-ray crystallography.
n-Decyl-ß-D-Maltoside, also known as DM, is a non-ionic detergent commonly used in crystallography to solubilize and stabilize membrane proteins for structural studies. It is particularly effective in extracting membrane proteins from lipid bilayers while maintaining their native structure and functionality.
Why is n-Decyl-ß-D-Maltoside preferred over other detergents for crystallography applications?
DM is preferred over other detergents for crystallography applications due to its mild and non-denaturing properties. It has a low critical micelle concentration, which means that it forms micelles at lower concentrations compared to other detergents, making it ideal for solubilizing membrane proteins without causing damage to their structure.
How does n-Decyl-ß-D-Maltoside help in crystallography experiments?
n-Decyl-ß-D-Maltoside plays a crucial role in crystallography experiments by effectively extracting membrane proteins from lipid bilayers, solubilizing them in a detergent micelle, and stabilizing their native structure. This allows for the purification and crystallization of membrane proteins for X-ray crystallography studies, ultimately leading to the determination of their three-dimensional structures.
What are the key advantages of using n-Decyl-ß-D-Maltoside in crystallography?
The key advantages of using n-Decyl-ß-D-Maltoside in crystallography include its non-denaturing properties, ability to solubilize membrane proteins effectively, low critical micelle concentration, and compatibility with various membrane protein systems. Additionally, DM is known for its stability and consistency, making it a reliable choice for researchers working on structural biology studies.
In summary, n-Decyl-ß-D-Maltoside is a versatile and effective detergent for crystallography applications, offering researchers a powerful tool for studying membrane proteins and unraveling their structures through X-ray crystallography.