Alcian Blue 8 GX (C.I. 74240) for clinical diagnosis

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Product Name Alcian Blue 8 GX
Chemical Composition C.I. 74240
Application Clinical Diagnosis
Staining Method Histological Staining
Dye Type Basic Dye
Appearance Blue Powder
Solubility Soluble in Water
PH Range 2.5-5.8
Specificity Selective for Acid Mucosubstances
Storage Store at Room Temperature
Hazard Statements Causes skin irritation. Causes serious eye irritation.
Precautionary Statements Wear protective gloves/eye protection/face protection. Wash hands thoroughly after handling. Avoid breathing dust/fume/gas/mist/vapors/spray.
Shelf Life 2 years
Manufacturer Various manufacturers available
FAQ
What is Alcian Blue 8 GX (C.I. 74240) and how is it used for clinical diagnosis?

Alcian Blue 8 GX (C.I. 74240) is a cationic copper phthalocyanine dye that is commonly used in histology and clinical pathology for the detection of acidic mucosubstances in tissues and cells. This dye is known for its binding affinity to glycosaminoglycans and acidic mucins, making it a valuable tool in the diagnosis of various diseases and conditions.

How does Alcian Blue 8 GX (C.I. 74240) work in clinical diagnosis?

Alcian Blue 8 GX (C.I. 74240) works by selectively staining acidic mucosubstances in tissues and cells. When applied to a specimen, the dye binds to glycosaminoglycans and acidic mucins, allowing for the visualization of these substances under a microscope. This staining technique helps pathologists and clinicians identify specific cellular components and abnormalities that may be indicative of certain diseases or conditions.

What are the main applications of Alcian Blue 8 GX (C.I. 74240) in clinical diagnosis?

Alcian Blue 8 GX (C.I. 74240) is commonly used in histopathology and clinical pathology for a variety of purposes, including the identification of cartilage, mucin-containing tissues, and mucopolysaccharides. It is frequently employed in the diagnosis of conditions such as mucopolysaccharidoses, cystic fibrosis, and various cartilage disorders. Additionally, Alcian Blue 8 GX (C.I. 74240) can be useful in differentiating between different types of mucins in tumors and assessing the degree of mucin production in cancerous tissues.

How is Alcian Blue 8 GX (C.I. 74240) applied in clinical practice?

Alcian Blue 8 GX (C.I. 74240) is typically used in histological staining procedures, where it is applied to tissue sections or cell samples to selectively stain acidic mucosubstances. The staining process involves fixing the specimens onto slides, applying the dye solution, rinsing off excess dye, and examining the stained samples under a microscope. By observing the blue staining pattern of acidic mucosubstances, pathologists can gain valuable insights into the composition and pathology of the tissues being studied.

What are the advantages of using Alcian Blue 8 GX (C.I. 74240) for clinical diagnosis?

The use of Alcian Blue 8 GX (C.I. 74240) in clinical diagnosis offers several advantages, including its high specificity for acidic mucosubstances, ease of application, and compatibility with various histological techniques. This dye is a valuable tool for identifying specific cellular components and abnormalities that may not be visible with other staining methods. Additionally, Alcian Blue 8 GX (C.I. 74240) can provide valuable diagnostic information in a wide range of pathological conditions, making it a versatile and reliable tool for clinicians and pathologists alike.
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